Endocrine Abstracts

Some literary data demonstrate that the twin defect of beta-cell failure and insulin resistance that underline T2DM can be reversed by acute negative energy balance alone. The aim of the present work was to assess treatment outcomes in women with new onset T2DM, who were previously diagnosed with GDM treated with acute dietary restriction or conventionally at 32 weeks postpartum (PP).Methods: In total 174 women with T2DM at 32 weeks PP, were enrolled in ...

Background: The Israeli-Georgian Program Diabetes in Pregnancy was initiated at the Georgian Diabetes Center in 1997, with the aim to provide care for women with diabetes. The Program has become possible as a result of Twinning between Union of Diabetes and Endocrine Association and Israeli Diabetes Association. It was initiated in 1997, and since then it successfully works, being the longest and most sustainable Twinning program in Europe. The aim to assess the efficacy of tr...

Background and aims: Components of metabolic syndrome (MS) carry an increased risk for cardiovascular disease (CVD). People with abnormal glucose regulation are more prone to develop complications. At diagnosis 20–30% of type 2 diabetic (T2DM) patients (pts) already have neuropathy-one of the most dangerous complications. Cardiac autonomic neuropathy (CAN) is associated with five-fold risk of mortality. Our aim was to study possible relation between CAN and some component...

Background: Hyperglycemia is believed to be the underlying cause for many of the adverse fetal, neonatal, and maternal outcomes in pregnancies complicated by type 1diabetes (T1DM). In particular, the rates of a large for gestational age (LGA) neonates and macrosomia remain high and suggest that hyperglycemia may not be the only driver of fetal overgrowth for women with T1DM.Aim: Our aim was to assess the association between gestational glycemic profiles ...

Background and aims: There are consistent findings about increased prevalence of depressive disorders in diabetes. The aim of the study was to reveal prevalence of depression in patients (pts) with type 1 (DM1) and type 2 (DM2) diabetes.Materials and methods: Totally, 157 pts with DM were questioned. To assess depression degree Beck’s scale was used, and 83 depressive pts (scores>10), were allocated into 2 groups (Gr.): Gr.1 (n=44)-DM2 pt...

Background and aims: The aim of this study was to study the effect of Nebivolol on clinical course and heart rate variability (HRV) parameters in type 2 diabetes (T2DM) patients (pts) with coronary heart disease (CHD) and Chronic heart failure (CHF) of III-IV FC.Materials and methods: Participants were 35 T2DM pts with CHD and CHF/ III-IV FC. The pts were divided into 2 groups (Gr.) Gr.1 (n=15, 10m/5f, mean age 59±7 years) on basic therapy. G...

Background and Aim: One of the greatest problem in pregnancy, complicated by diabetes is screening and appropriate care for women, whose diabetes is manifested during pregnancy. The study is aimed at gathering epidemiological data on gestational diabetes mellitus (GDM) and evaluating the of appropriate therapy in this condition.Materials and Methods: Screening for GDM was carried out in – 692 pregnant women. GDM was observed in 3.3% (22 women) and i...